The effects of the specific 5HT4 receptor agonist, prucalopride, on colonic motility in healthy volunteers
نویسندگان
چکیده
منابع مشابه
Selective stimulation of colonic transit by the benzofuran 5HT4 agonist, prucalopride, in healthy humans.
BACKGROUND Prucalopride (R093877) is a selective and specific 5HT4 agonist, the first of a new chemical class of benzofurans, with gastrointestinal prokinetic activities in vitro. AIMS To evaluate the effects of prucalopride on gastrointestinal and colonic transit. METHODS A validated scintigraphic technique was used to measure gastrointestinal and colonic transit over 48 hours in 50 health...
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ژورنال
عنوان ژورنال: Alimentary Pharmacology & Therapeutics
سال: 2002
ISSN: 0269-2813
DOI: 10.1046/j.1365-2036.2002.01195.x